陈文:云南大学化学科学与工程学院副研究员-中文百科频道

人物经历

2008年7月获云南民族大学理学学士学位；

2011年7月获云南民族大学理学硕士学位；

2014年12月获云南大学理学博士学位；

2015年7月至今，云南大学工作。

教学课程

承担多名本科生毕业论文指导工作

研究领域

复杂天然产物的不对称全合成

学术成果

论文、专著

Chen, W., Yang, X. D., Tan, W. Y., Zhang, X. Y., Liao, X. L., & Zhang, H. Total Synthesis of (−)‐Vindorosine. Angewandte Chemie International Edition,2017, 56(40):12327-12331. Wen Chen, Hongbin Zhang, Asymmetric construction of all-carbon quaternary stereocenters in the total synthesis of natural products, Science China Chemistry 2016, DOI: 10.1007/s11426-016-0055-0. Wen Chen, Jian Ren, Minshou Wang, Lingjing Dang, Xianfu Shen, Xiaodong Yang Hongbin Zhang, Iodine mediated deprotection of N-tert-butanesulfinyl amines: a functional group compatible method, Chemical Communications 2014, 50, 6259-6262. Wen Chen, Xiao-Dong Yang, Yan Li, Li-Juan Yang, Xue-Quan Wang, Gao-Lan Zhang, Hong-Bin Zhang, Design, synthesis and cytotoxic activities of novel hybrid compounds between dihydrobenzofuran and imidazole, Organic & Biomolecular Chemistry 2011, 9, 4250-4255. Wen Chen, Xiao-Yan Deng, Yan Li, Li-Juan Yang, Wei-Chao Wan, Xue-Quan Wang, Hong-Bin Zhang, Xiao-Dong Yang, Synthesis and cytotoxic activities of novel hybrid 2-phenyl-3-alkylbenzofuran and imidazole/triazole compounds, Bioorganic & Medicinal Chemistry Letters 2013, 23, 4297-4302. Wen Chen, Li-Juan Yang, Shui-Xian Ma, Xiao-Dong Yang, Bao-Min Fan, Jun Lin, Crassicauline A/β-Cyclodextrin host–guest system: Preparation, characterization, inclusion mode, solubilization and stability, Carbohydrate Polymers, 2011, 84, 1321-1328. Wen Chen, Li-Juan Yang, Yan Li, Xue-Quan Wang, Shao-Jie Wang, Wei-Chao Wan, Hong-Bin Zhang, and Xiao-Dong Yang, Novel Tricyclic Indenofuran -imidazole Hybrid Compounds: Design, Synthesis and Antitumor Activity, Letters in Drug Design & Discovery 2013, 10, 561-571. Wei-Chao Wan, Wen Chen, Lan-Xiang Liu, Yan Li, Li-Juan Yang, Xiao-Yan Deng, Hong-Bin Zhang, Xiao-Dong Yang, Synthesis and cytotoxic activity of novel hybrid compounds between 2-alkylbenzofuran and imidazole, Medicinal Chemistry Research 2014, 23, 1599-1611. (共同第一作者) Shui-Xian Ma, Wen Chen, Xiao-Dong Yang, Na Zhang, Shao-Jie Wang, Lin Liu, Li-Juan Yang, Alpinetin/hydroxypropyl-cyclodextrin host-guest system: Preparation, characterization, inclusion mode, solubilization and stability, Journal of Pharmaceutical and Biomedical Analysis, 2012, 67-68: 193-200. (共同第一作者) Li-Juan Yang, Wen Chen, Shui-Xian Ma, Yun-Tao Gao, Rong Huang, Sheng-Jiao Yan, Jun Lin. Host–Guest System of Taxifolin and Native Cyclodextrin or Its Derivative: Preparation, Characterization, Inclusion Mode, and Solubilization, Carbohydrate Polymers 2011, 85, 629-637. (第一作者为导师) Li-Juan Yang, Wen Chen, Yi-Ping Luo, Gan-Peng Li, Xiao-Dong Yang, Liang Li, Lignans and ketonic compounds from Litsea chinpingensis, Biochemical Systematics and Ecology 2009, 37, 696-698. (第一作者为导师)

科研项目、成果和专利

1.卤代吖丙啶类化合物的不对称合成及其抗肿瘤活性研究，云南省应用基础研究计划(2016FD007)，2016.9-2019.9。（负责）

2. 羊晓东，张洪彬，陈文，汪学全，杨丽娟，李良，二氢呋喃并茚烷-咪唑盐类化合物及其制备方法，CN201210237387.3，申请时间：2012年7月9日。

3. 羊晓东，张洪彬，汪学全，陈文，李良，刘建平，2-苄基取代苯并呋喃—咪唑盐类化合物及其制备方法，CN201210237371.2，授权时间：2014年10月15日。