人物經曆
1998.6 - 迄今：首都師範大學生命科學學院，教授（1999-2009期間擔任生物系系主任/院長;2008-2017年期間擔任首都師範大學副校長）
2002.1 - 2003.6/2010.1 - 2010.5：美國杜克大學（DCMB/Biology, Duke University, USA），訪問學者
1999.7-1999.10：日本STA Fellowship資助，“日本岩手生物技術研究中心”客座研究員
1996.2 - 1998.9：中科院遺傳所“負壓室” (現“植物基因組國家重點實驗室”) 804組，博士後
1992.9-1995.12：東北師大“細胞與遺傳研究所”博士（植物細胞遺傳方向）
1985.9 - 1988.7：東北師大生物系，碩士（植物細胞工程方向）
1982.2 - 1992.7：南充師範學院生物系，助教、講師、副教授
1978.3 - 1982.2：南充師範學院（現: 西華師範大學）生物系，學士
主要成就
科研成就
1. 國家自然科學基金重大研究計劃,項目編号91631109,銀葉真藓适應極端環境的基因組特征及關鍵基因的作用機制（2017.01-2019.12）
2. 國家自然科學基金重點項目，項目編号31530006，拟南芥一氧化氮合酶(NOS)解析及NO信号途徑對(水分)脅迫的應答（2016.01-2020.12）
3. 國家自然科學基金面上項目，項目編号31470357，小立碗藓水分脅迫應答中通過miRNA66調控ABA平衡的分子機制（2015/01-2018/12）
4. 國家“轉基因生物新品種培育科技重大專項”， 項目編号2014ZX0800923B，苔藓等抗幹旱主效基因或元件的克隆與功能分析（2014/01-2016/12）
5. 國家“轉基因生物新品種培育科技重大專項”，項目編号2009ZX08009-058B，極端生境藓類抗逆 (幹旱等)“主效”基因/調控元件分離及功能驗證（2009-2010）
6. 國家重大科學研究計劃，項目編号2007CB948201，植物生長點幹細胞的維持機制（2007-2011）
7. 國家高技術研究發展計劃（863計劃），項目編号2007AA021405，特殊低等植物抗逆基因的開發利用（2007-2010）
8. 北京市自然科學基金重點項目 (B類)，項目編号Z200610028017，小立碗藓脅迫應答蛋白組分析及抗逆基因分離 （2005-2008）
9. 國家傑出青年基金 (B類項目—海外青年學者合作研究基金)，項目編号30328003，高等植物中Ca2+與NO相互作用分子調控機理（2004-2006）
10. 北京市自然科學基金重點項目，項目編号5021001，極端生境藓類代表種的功能基因組分析及抗逆基因克隆（2002-2005）
論文
1. Wang J*, Wang Y, Lv Q, Wang L, Du J, Bao F, He YK*(2017). Nitric oxide modifies root growth by S-nitrosylation of plastidial glyceraldehyde-3-phosphate dehydrogenase. Biochem Biophys Res Commun. 488(1): 88-94. doi: 0.1016/j.bbrc.2017.05.012
2. Wang L, Kong D*, Lv Q, Niu GQ, Han T, Zhao X, Meng S, Cheng Q, Guo S, Du J, Wu Z, Wang J, Bao F, Hu Y, Pan X, Xia J, Yuan D, Han L, Lian T, Zhang C, Wang H, He XJ, He YK (2017). Tetrahydrofolate modulates Floral Transition through Epigenetic Silencing. Plant Physiol. doi: 10.1104/pp.16.01750
3. Wang X*, Chen L, Yang A, Bu C, He Y*(2017). Quantitative Proteomics Analysis of Developmental Reprogramming in Protoplasts of the Moss Physcomitrella patens. Plant Cell Physiol. 58(5): 946-961. doi: 10.1093/pcp/pcx039.
4. Niu G, Zhao S, Wang L, Dong W, Liu L, He Y*(2017). Structure of the Arabidopsis thaliana NADPH-cytochrome P450 reductase 2 (ATR2) provides insight into its function. FEBS J. 284(5): 754-765. doi: 10.1111/febs.14017
5. Shu Yuan*, Zhongwei Zhang, Chong Zheng, Zhongyi Zhao, Yu Wang, Lingyang Feng, Guoqi Niua, Changquan Wang, Jianhui Wang, Hong Feng, Fei Xu, Fang Ba, Yong Hu, Ying Cao, Ligeng Ma, Haiyang Wang, Dongdong Kong, Wei Xiao, Honghui Lin, and He Yikun* (2016). Arabidopsis cryptochrome 1 functions in nitrogen regulation of flowering. Proc Natl Acad Sci USA 113(27): 7661-7666
6. Zhou YH, Zhang ZW, Zheng C, Yuan S, He Y (2016). Nitrogen regulates CRY1 phosphorylation and circadian clock input pathways. Plant Signal Behav. 11(9):e1219830. doi: 10.1080/15592324.2016.1219830.
7. Xia J, Wang X, Perroud PF, He Y, Quatrano R, Zhang W*(2016). Endogenous Small-Noncoding RNAs and Potential Functions in Desiccation Tolerance in Physcomitrella Patens. Sci Rep. 2016 Jul 22; 6:30118. doi: 10.1038/srep30118.
8. Xiao L., Yang G., Zhang L., Yang X., Zhao S., Ji Z., Zhou Q., Hu M., Wang Y., Chen M., Xu Y., Jin H., Xiao X., Hu G., Bao F., Hu Y., Wan P., Li L., Deng X., Kuang T., Xiang C., Zhu JK*, Oliver M.J., He Yikun* (2015). The resurrection genome of Boea hygrometrica: A blueprint for survival of dehydration. Proc Natl Acad Sci USA 112(18): 5833-5837.
9. Zhang F., Han M., Lv Q., Bao F., He Yikun* (2015). Identification and expression profile analysis of NUCLEAR FACTOR-Y families in Physcomitrella patens. Front. Plant Sci. 6, 642. http://doi.org/10.3389/ fpls.2015.00642
10. Tian W., Hou C., Ren Z., Pan Y., Jia J., Zhang H., Bai F., Zhang P., Zhu H., He Yikun, Luo S.*, Li L.*, Luan S.* (2015). A molecular pathway for CO2 response in Arabidopsis guard cells. Nature communications 6: 6057, doi: 10.1038/ncomms7057.
11. Xia J., Kong D.*, Xue S., Tian W., Li N., Bao F., Hu Y., Du J., Wang Y., Pan X. Wang L., Zhang X., Niu G., Feng X., Li L., He Yikun*(2014). Nitric oxide negatively regulates AKT1-mediated potassium uptake through modulating vitamin B6 homeostasis in Arabidopsis. Proc Natl Acad Sci USA 111: 16196-16201.
12. Yuan F.*, Yang H., Xue Y., Kong D., Ye R., Li C., Zhang J., Theprungsirikul L., Shrift T., Krichilsky B., johnson D.M., Swift G.B., He Yikun, Siedow J.N., Pei Z.*(2014). OSCA1 mediates osmotic-stress-evoked Ca2+ increases vital for osmosensing in Arabidopsis. Nature 514: 367-371.
13. Xiaoqin Wang, Sa Zhou, Lu Chen, Ralph S. Quatrano, Yikun He* (2014). Phospho-proteomic analysis of developmental reprogramming in the moss Physcomitrella patens. J Proteomics 108:284-294
14. Xiaoqin Wang, Meiyan Qi, Jingyun Li, Zhongzhong Ji, Yong Hu, Fang Bao, Ramamurthy Mahalingam & Yikun He*(2014).The phospho-proteome in regenerating protoplasts from Physcomitrella patens protonemata shows changes paralleling postembryonic development in higher plants. J Exp Bot 65 (8): 2093-2106.
15. Du J, Li M, Kong D, Wang L, Lv Q, Wang J, Bao F, Gong Q, Xia J, He Yikun*(2014). Nitric oxide induces cotyledon senescence involving co-operation of the NES1/MAD1 and EIN2-associated ORE1 signalling pathways in Arabidopsis. J Exp Bot, 65(14): 4051-4063.
16. Weizhong Liu, Dongdong Kong, Xuexin Gu, Hongbo Gao, Jinzheng Wang, Mi Xia, Qian Gao, Lili Tian, Zhanghong Xu, Fang Bao, Yong Hu, Nengsheng Ye, Zhenming Pei, Yikun He*(2013). Cytokinins can act as suppressors of nitric oxide in Arabidopsis. Proc Natl Acad Sci USA，110: 1548-1553
17. Bai S.*, Yao T., Li M., Guo X., Zhang Y., Zhu S., He Yikun*(2014). PIF3 is involved in the primary root growth inhibition of Arabidopsis induced by nitric oxide in the light. Mol Plant 7: 616-625.
18. Lihong Xiao, Liechi Zhang, Ge Yang, Honglin Zhu, Yikun He*(2012). Transcriptome of protoplasts reprogrammed into stem cells in Physcomitrella patens. PLoS ONE，7: e35961
19. Sulan Bai, Miaomiao Li, Tao Yao, Hui Wang, Yaochuan Zhang, Lihong Xiao, Jinzheng Wang, Zhen Zhang, Yong Hu, Weizhong Liu, Yikun He*(2012). Nitric oxide restrain root growth by DNA damage induced cell cycle arrest in Arabidopsis thaliana. Nitric Oxide - Biology and Chemistry，26: 54-60
20. Suxia Cui*, Jia Hu, Shilei Guo, Jie Wang, Yali Cheng, Xinxing Dang, Lili Wu, Yikun He*(2012). Proteome analysis of Physcomitrella patens exposed to progressive dehydration and rehydration. Journal of Experimental Botany，63: 711-726
21. Lihong Xiao, Hui Wang, Ping Wan, Tingyun Kuang, Yikun He*(2011). Genome-wide transcriptome analysis of gametophyte development in Physcomitrella patens. BMC Plant Biology, 11: 177 http://www.biomedcentral.com/1471-2229/11/177
22. Xiaoqin Wang, Tingyun Kuang, Yikun He*(2010). Conservation between higher plants and the moss Physcomitrella patens in response to phytohormone abscisic acid: analysis by proteomics approach. BMC Plant Biology, 10: 192 http://www.biomedcentral.com/1471-2229/10/192
23. Xiaoqin Wang, Zheng Liu, Weizhong Liu, Yong Hu, Hui Chen, Tingyun Kuang, Shihua Shen*, Yikun He*(2009). Proteomic analysis of cold stress response in the moss Physcomitrella patens. Proteomics, 9: 4529-4538
24. Min Zhang, Yong Hu, Jingjing Jia, Dapeng Li, Runjie Zhang, Hongbo Gao*, Yikun He*(2009). CDP1, a novel component of chloroplast division site positioning system in Arabidopsis. Cell Research, 19: 877-886
25. Min Zhang, Yong Hu, Jingjing Jia, Hongbo Gao*, Yikun He*(2009). A plant MinD homologue rescues Escherichia coli HL1 mutant (Delta MinDE) in the absence of MinE. BMC Microbiology, 9: 101 doi:10.1186/1471-2180-9-101
26. Xiaoqin Wang, Pingfang Yang, Zheng Liu, Weizhong Liu, Yong Hu, Hui Chen, Tingyun Kuang, Zhenming Pei, Shihua Shen, Yikun He*(2009). Exploring the mechanism of Physcomitrella patens desiccation tolerance through a proteomic strategy. Plant Physiology, 149: 1739-1750
27. Xiaoqin Wang, Yikun He*(2009). Negative effects of desiccation on the protein sorting and post-translational modification. Plant Signaling & Behavior, 4: 435-437
28. Jinchan Xia, Huan Zhao, Weizhong Liu, Legong Li*, Yikun He*(2009). Role of cytokinin and salicylic acid in plants growth at low temperatures. Plant Growth Regulation, 57: 211-221
29. Suxia Cui, Jia Hu, Bin Yang, Lu Shi, Fang Huang, Sau-Na Tsai, Sai-Ming Ngai, Yikun He, Jianhua Zhang* (2009). Proteomic characterization of Phragmites communis in ecotypes of swamp and desert dune. Proteomics, 9: 3950-3967
30. Shaowu Xue, Pin Yang, Yikun He*(2008). Nitric oxide suppresses stomatal opening by inhibiting inward-rectifying K+ in channels in Arabidopsis guard cells. Chinese Science Bulletin, 53: 2156-2159
31. Yong Hu, Zhiwei Chen, Weizhong Liu, Weiwei Zhou, Yikun He*(2008). Chloroplast division regulated by the circadian expression of FtsZ and Min genes in Chlamydomonas reinhardtii. European Journal of Phycology, 43: 207-215
32. Xiaoqin Wang, Pingfang Yang, Qian Gao, Tingyun Kuang, Shihua She*, Yikun He*(2008). Proteomic analysis of the response to high-salinity stress in Physcomitrella patens. Planta, 288: 167-177
33. Xiaoqin Wang, Zheng Liu, Yikun He* (2008). Responses and tolerance to salt stress in bryophytes. Plant Signaling & Behavior, 3(8): 516-518
34. Cheng Liu, Yajie Zhang, Derong Cao, Yikun He, Tingyun Kuang, and Chunghong Yang* (2008). Structural and functional analysis of the anti-parallel strands in the lumenal loop of the major light-harvesting chlorophyll a/b complex of photosystem II (LHCIIb) by site-directed mutagenesis. J.Boil.Chem, 283(1): 487-495
35. Ming-Ming Sun, Lin-Hui Li, Hua Xie, Rong-Cai Ma, Yikun He* (2007). Differentially Expressed Genes under cold acclimation in Physcomitrella patens. J. of Biochemi. and Mol Bio., 40(6): 986-1001
36. Ning Liu, Nai-Qin Zhong, Gui-Ling Wan, Li-Juan Li, Xiang-Lin Liu, Yi-Kun He*, Gui-Xian Xia*(2007). Cloning and functional characterization of PpDBF1 gene encoding a DRE-binding transcription factor from Physcomitrella patens. Planta. 226(4): 827-838
37. Weizhong Liu, Yong Hu, Runjie Zhang, Weiwei Zhou, Jiaying Zhu, Xianglin Liu, Yikun He*(2007). Transfer of a eubacteria-type cell division site-determining factor CrMinD gene to the nucleus from the chloroplast genome in Chlamydomonas reinhardtii. Chinese Bulletin of Science, 52: 2514-2521
38. Lin-Hui Li, Xian-Ping Wang & Yi-Kun He*(2005). An efficient protocol for plant regeneration from protoplasts of the Moss Atrichum ndulatum P. Beauv in vitro. Plant Cell, Organ and Tissue Culture, 82: 281-288
39.Yikun He, Ruhang Tang, Yi Hao, Robert D. Stevens,Charles W. Cook,Sun M. Ahn, Liufang Jing, Zhongguang Yang, Fangqing Guo, Longen Chen,Fabio Fiorani, Robert B. Jackson, Nigel M. Crawford, Zhenming Pei* (2004). Nitric oxide represses the Arabidopsis floral transition. Science, 305: 1968-1971
榮譽表彰
在植物細胞逆境應答研究領域取得了系列學術成果，以責任作者在PNAS，Plant Physiology，Cell Research，JXB，Proteomics，Nitric Oxide - Biology and Chemistry等國際學術刊物上發表研究論文50餘篇，在NO調控植物開花研究領域做出了開創性工作（Science, 2004）。
應“科學出版社”之邀，主編出版高等師範院校新世紀教材《細胞生物學》（2009年出版）。2005、2009年2次獲北京市教育教學成果(高等教育)獎二等獎。2005年獲“北京市先進工作者”稱号。2006年被評為北京市高校創新拔尖人才。2007年獲北京市高等學校教學名師獎。
社會任職
中國植物學會常務理事（2003-），北京市細胞生物學學會副理事長（2011-），國家自然科學基金委學科評議組成員（2006-2009），教育部高等學校生物學基礎課程教學指導委員會委員（2006-2010）、第三屆學科發展與專業設置專家委員會委員（2011-2014）、大學生物學課程教學指導委員會副主任委員（2013-2017），《生物學通報》常務編委（2007-），《植物學報》編委（2007-），中科院植物研究所北方植物資源重點實驗室學術委員會委員（2013-），中科院植物研究所分子生理學重點實驗室學術委員會委員（2016-）。
